Resident Publication – Dr. Martin Smoragiewicz

Dr. Smoragiewicz was a part author of a paper published in Cancer, “Risk Factors and Model for Predicting Toxicity-Related Treatment Discontinuation in Patients With Metastatic Renal Cell Carcinoma Treated With Vascular Endothelial Growth Factor–Targeted Therapy: Results From the International Metastatic Renal Cell Carcinoma Database Consortium“. They found that age, glomerular filtration rate, number of metastatic sites, and baseline sodium level were found to be independent risk factors for toxicity-related treatment discontinuation (TrTD) in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-targeted therapy. Based on the number of risk factors present, they built a model for predicting TrTD to be used as a tool for toxicity monitoring in clinical practice.

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author: Michelle Seymour